The prophecies of Isaiah have not happened yet. I believe there will not be a big ground war until Armageddon, I do think Israel will get massively attacked and expend it's entire NBC arsenal. That would reek the kind of destruction the Bible speaks of.
But the Bible says that the Jews also will be among the attackers of Jerusalem, and thus also among the reapers of the prophesied punishments.
"Even Judah will fight against Jerusalem." Jeremiah 14,14. Makes no sense unless Jerusalem is a metaphor for the Church. Just so happens that this is the understanding of Christianity going back two-thousand years.
