My late father drilled a deer broadside through the chest cavity with a first generation Ballistic Tip, a 130 grain powered by a full charge of H4831 from a 26" barreled 270. The distance was inside 200 yards IIRC.
Dad was impressed by the liquefied thoracic contents blown out of the far side of the deer, and by the distance the deer was able to run despite having mush for plumbing.
I think Ingwe would say that the problem is obvious - 270!