Any more I find myself gravitating toward the .308 or '06 family of cartridges, and the odd AI version thereof. I find that speed is not everything, and isn't needed for most of what I do. These have good brass availability and interchangeability if needed, mild recoil, will fit in common actions., and so on. And if you neck size you can get away with a handful of sizing dies and just buy different bushings.
Sometimes simple is better, and less is more. But I still have a wildcat or two on the WSM case and a hankering for a 7 SAUM. Just because I've never had one.
