I like something that can be fun to shoot, kill well at reasonable ranges, and is a little different (although I like to have one rifle chambered to a common cartridge to bring on out of state hunts as back up).
Generally that means non-magnum "classic" cartridges or their modern equivalents: .257 Rob/.25-06, 6.5x55/260, 7x57/7-08/.280, .308/.30-06, etc.
Accuracy and enjoyability trump speed every time, and massive blast really messes with my ability to shoot well.
