Allow me to explain.....sitting on clearcuts (first light and last light), with shots out to 500+, I have the 165's in the rifle. Mid-day, still hunting the black timber, I have the 220's in. Where I hunt whitetails, here in Idaho, there is not much "in between" country, and I only swap ammo once I'm set up to glass the clearcuts. Never had the problem of having the wrong ammo in at the wrong time....and like I said, I only do this with the one rifle, because of the POI of the two loads, in relation to each other. I do have other dedicated long range rifles and timber guns, that I use too. The '06 allows me to do the same with one rifle with the 2 loads. Andy 3