I own both and have used them for years hunting Newfoundland, which mimics Alaska's boreal forest and barren grounds terrain amazingly close. I've taken many woodland caribou, Canadian moose and uber large black bears that can grow as large as 700+ lbs. I generally prefer my own handloads (160gr Barnes Triple Shock for 7mm Rem Mag & 180gr Nosler Partition for the .30-06) but I'd have no reservations betting my moose hunt on 175gr Core-Lokts in factory ammo. As much as I love the 7mm Rem Mag, however, if I was hunting Brown bears, I'd probably opt for the '06 simply because I'd prefer to use a heavier bullet on dangerous game.
Regardless of calibre, I think the most important consideration is what rifle and calibre each individual shoots best. Whether you're shooting a 100gr pill from a .243Win or a 220gr bullet out of your grandfather's old Springfield, put it in the boiler room of even the largest moose and the result is the same.
