I've bought and retrofitted around 7-8 10/22's and found them perfectly fitted for shooting jack rabbits on the run, multiple ground squirrels, large rock chucks, skunks, and crows due to their accuracy and firepower.
Using target grade barrels has helped in the accuracy department as well as some judicial trigger work.
For all out accuracy, but not necessarily in the hunting mode, my Biathlon rifle is king. Bedded action, floated barrel and around a 1.5# trigger are winners.
However I hunt more than a shoot competitive so the winner is still the 10/22.
