Just fyi for anyone else, I loaded up the 165 BTs for a friend's .308. He hadn't hunted in 20 yrs. Shot a 10pt buck in rear of lungs @ 150yds. Blew out back side on exit, left a red carpet for 30 yds to where we found him. I rarely had an exit with the 300wby. Seemed to pentetrate lungs about 2-3 inches and explode turning everything to jelly and DRT. Would usually find end of cup against opposing hide and frag bits scattered.