Sure seems like the whole "killing African game" thing gets way overthunk. We're not curing cancer here, just killing critters that are mere mortals, just like every other big game animal. Use a good quality bullet out of a rifle you would normally use on any big game(and most importantly.....shoot very well!) Most importantly; place your shot where it needs to land, and you're done! We've used a 9.3x74R on the large end, and a 7-08 on the small end. Everything died. Have friends who have used many cartridges in between......same result. A reasonably constructed bullet placed with care. That's a standard plains game(or any big game) rig. Obviously, you don't want to hunt the larger PG like eland with .222. Just use some common sense and go for it.

Jeff