I think regardless of the firearm, .22 LR is one of the most versatile and necessary rounds made. It can take small game in ANY setting and if we, God forbid, end up with a situation where ammo would be one of the more barterable items, it would certainly be advantageous to have several thousand rounds of .22 LR in your pack. A .22 LR would be preferable to a quite a few other rounds due to ease of shooting, the amount of rounds you can carry without overburdening your pack, and plenty of people have been killed by .22 LR rounds. Think someone would keep trying to attack you if you shot him in the face 5 or 6 times with a .22 LR? I led off with "regardless of the firearm", and I probably should modify that. I think a 1911 in 45 ACP with a .22 LR conversion kit would be firearm for all situations, as an example. I'm sure other combinations would work well also.