The main use I'd have for 4451 now would be for 90gr e-tips in my.243, but I've got a bunch of other stuff to burn up, so I may not get to to it. RL26 is looking good for 100gr and up bullets. Used 45gr under a Sierra PH last year to whack a doe, and if I get that far in my rotation, 103gr ELD-Xs over a bit more will get a turn this season in my fast-twist Number 1V. Might have to hire a crew to carry it for me, though!
Another new one I'm liking is CFE223, in the .308, and eventually maybe in the CZ Grendel that I'm picking up tomorrow. Pretty impressive, according to the data I've seen, though for some reason Hodgdon doesn't list it for that round, in the printed manual anyway.
