.[/quote]
I don't recommend pulling off a snap shot at animals over 400, even with some behemoth overbore. Seems like an opportunity for a rodeo. Long shots require a precision that takes a few breaths and more than a few seconds to get right.[/quote]

I agree and I usually can pre-range a marker at 350 or 400 and that is my limit unless I can stop the buck and settle in to the shot. Tough passing on a twelve pointer within your scope but the cross hairs just didn't settle in enough to be sure. Basically what has worked and I probably should stick with it is any bullet with a 400+ BC and around 3200 fps.
The 25-06, 270 WSM, 280AI, 7RM & 300WM all do this with my loads. Working up R26 loads for the 243 and 6AI that should fit the bill with 95-110 grain bullets.

"When you disarm the people, you commence to offend them and show that you distrust them either through cowardice or lack of confidence, and both of these opinions generate hatred." Niccolo Machiavelli