I can't comment first hand on the stopping ability between a .416 and a .458, but I personally wouldn't hesitate with either.
I like the CZ's. They are just big and heavy. Riding around in a Land Rover, I'm sure they are great. Crawling through Alaskan brush with 10#'s of gun and 25" of barrel, maybe not so much. Chop the barrel at 20" and put it in a decent synthetic and it would probably be great.
I might be tempted to find a PF or classic M70 in 458 and do the same to it. I like M70 triggers and likely more stock choices inletted for a Win M70 .