I love the 250 Savage, and used to have one in a Tang Safety Ruger 77 RSI. I think it's the lightest-kicking, all-around deer-capable round out there.
Personally, if I wanted to go to a 250 ai, I'd get a 6.5 Creeedmoor. I think the 250/3000 is "just right" as is.
Were I building one I'd fine a used Kimber 84M (blued/walnut) and do a rebarrel. Or a Kimber MT and do likewise.