I'd love to have a 280, but already have a 7-08.
I may be missing out on some recoil and fps, but the critters I shoot dont notice the difference.
also.... the 7-08 is miserly on powder, and it being a short action, is marginally lighter in rifle form.
the downside to the 7-08 is that my 13 year old son discovered it and has absolutely taken over. little fart shot a buck, two pigs and a bobcat this season. his only miss was a coyote at 150 yds, running. everything else died quick.
every time we hunt, he's carrying it. I'm stuck carrying the 243 or 308, missing "my" old rifle. first world problems.
all that to say..... the 7-08 works.