I've had great results with the 200grn Speers on deer and certainly wouldn't give it another thought about using them on elk. I've never caught one in a deer.
This past season's buck was shot with a 180AB at about .338 Fed velocities. Though it worked, I was expecting more from it.
The bullet hit near the last ribs and angled to the opposite shoulder, coming to rest under the hide. Never hit any bone. The entrance looked like a part in the hair without a single drop of blood anywhere. Recovered bullet expanded very wide and weighed 153grns. IMO, it expanded too wide and acted like a parachute.
Example of one.
