Due to feral culling I've had the opportunity to hundreds animals per week, and much of that was done with 30-06s over a few years. There's no way I was going let a chance like that go by without comparing bullets. It would be hard not to, even if you hadn't started with that plan.
By the time I'd used up the stockpile there was no doubt that the Barnes (In my case the 168 TSX) was the slowest killing and best penetrating of the bunch. For your use of 425 yard tops deer and elk I'd use just about anything else first.
