I don't hunt with Barnes bullets, and have little experience. But my cousin shoots them in his 06, and he had a moose tag here in Montana. I called a nice bull in for him, and he shot it broad side at 75 yds. He shot it behind the shoulder,and gave him 1 more because his guide told him to. The bull only made it 20 yds. Two exit holes about the size of a quarter, internal damage, why sufficient, was not extensive. Any bullet through the lungs would have killed the moose at that range, but the Barnes worked as advertised. I think it was 165 gr. Just 1 observation, take it for what it is worth. Hope it helps.