You'll see more improvement in your groups getting runout down from .008" to .002" than you will doing things like weighing charges to the nearest tenth of a gnat's ass.
Yup.
FWIW, I'm a innanet nobody, kind of a hunter, not a shooter, and definitely not a gun writer. Still, even I can see a difference in groups with .003 runout and above.
Also, in my experience, naturally straight, vs. straightened with a Tru-Angle tool, makes no difference.The F-class guys might have different answers, but those are mine.
Good Luck,
FC