The 52gr Speer Varminter has been my goto bullet for most of my pelt hunting for decades, it has worked well in my 222 Rem, 5.6x50R Mag, and 22-250, it seems to work well over a large range of velocities. I've used the 50gr NBT at lower velocities in a 223 with some success but went back to the Speer because it was easier to find during the component shortage. I do have one little rifle in 22-204 that dotes on 40gr NBT's at around 4000 fps that I do a lot of pelt hunting with also.
Speer 52gr FB HP Varmint (I buy these a "K" at a time)
https://www.speer-ammo.com/bullets/rifle-bullets/varminter-hollow-point-bullets/224/224-52-hp-bullet
