I've never used the 165 .30 GK at all that I can recall, but have used the 160 7mm in the 7x57 considerably, handloaded to around 2700 fps. Have never had any difficulty with them at that velocity, but have had with other GameKings at around 2900 or so. But this is pretty much true of cup-and-core bullets, with the exception of Hornady Interlocks.
I suspect the muzzle velocity in factory .30-06 loads would be around 2800 fps, which would probably work OK on deer-sized game, but wouldn't be my first choice on anything larger.
