If you are hunting in Colorado, the Minimum Cartridge/Caliber question has been answered for you, by the Colorado Dept. of Parks and Wildlife:
1. CENTERFIRE RIFLES a. Must be a minimum of .24 caliber (6 mm). b. Must have a minimum 16-inch barrel and be at least 26 inches long. c. If semiautomatic, a maximum of six rounds are allowed in the magazine and chamber combined. d. Must use expanding bullets that weigh a minimum of 70 grains for deer, pronghorn and bear, 85 grains for elk and moose, and have an impact energy (at 100 yards) of 1,000-ft.-pounds as rated by manufacturer.
Their brochure doesn't list a maximum caliber restriction, so I guess if you want to use your .460 Weatherby, it's your call.......
I'd rather be a free man in my grave, than living as a puppet or a slave....