Have shot a pile of big game with 200-grain .30 caliber Partitions, many of them bull elk at least as large as an interior grizzly, both from the .30-06 and three .300 magnums. They don't always exit, but usually do. One example was a 6x6 bull at 75 yards, quartering toward me. Shot it through the big shoulder joint with a handload from the .300 Winchester Magnum with a muzzle velocity right around 3000 fps. The bullet smashed the shoulde and exited at the rear of the ribcage on the other side. Elk pretty dead, pretty fast.
