In an effort not to re-litigate this tired argument, merely running the .45 Colt up to the .44Mag’s SAAMI max of 36,000 psi, with same weight bullets will result in a good 150 - 200 fps velocity advantage over the .44 Mag. It’s just physics. I know some will cite load data that stops at about 30,000 psi for “Ruger-only” loads, but for a true apple to apple comparison, you have to run the same pressures. I had some 335 grain .45 Colt loads pressure tested at 36,000 psi and out of a real loose (had a large cylinder gap) SRH in .454, they would consistently run over 1,400 fps. This will be my first and last post on the topic in this thread.