I'm having another thought about reasons to not use small calibers in bad weather, or thick and heavy cover.
Imagine you and your buddies are back at camp cooking dinner after a cold misty day. The last man comes in after dark and before you have eaten, and says hey everybody will you help me look for a wounded deer, I seen him buck at the shot but can't find him?
Are your thoughts likely to be more enthusiastic toward spending a couple of hours in wet brush with a flash light if the hunter used a .243 or a .308?
