I prefer the dirty thirty. But have shot plenty of deer with the .44mag. using cheap Winchester white box 240s as well Hornady leverevolution 225s.
My dad has taken bucks at 191 yards and 157 yards with the leverevolution loads as well. Both dropped within twenty yards and were pass through double lung shots.
-Jake
Pretty easy to take deer out to 250 with a coped 30-30 if sighted about 3 inches high at 100. That's about where I sight my flat shooters for dead on at 300 or so.