To me the 338/06 was at it's best...IMHO with 200 NBTs for deer and similar game, and 225 PTs for everything else.

In the 338 Federal, My belief is the round shines with 185 - 210s. The 185 Barnes and 200 Sp loads can do a lot of killing within the window of this round, which I would put out to around 300 yds, same size game as any other 33 bore, like the Win Mag. I'd use a Mono or PT on anything really big and/or dangerous. Just me. Lighter bullets give up BC so sizzle out faster downrange, heavier bullets don't fly as flat.

What range you shoot and game does matter. 200 BTs are long and might rob capacity in this SA round.