Looks like most stuff has been covered already, but will comment that case life when using Li'l Gun (and a really good alternative, Alliant 300-MP) is REALLY good, because they attain top velocities at far lower pressures than traditional Hornet powders like 2400 and H110.
Have also found that the CCI-450 small rifle magnum primer attained the best accuracy in my rifle with 300-MP, along with Li'l Gun. But it's always worthwhile to try at least 3 primers in such small cases. They seem to be more senistive to primer changes than larger cartridges. Might also note that in my .17 Hornady Hornet, the CCI 450 was not the most accurate primer, even though I also use what are very slow-burning powders for it. Instead the Remington 7-1/2 works best.
