szihn, Thanks for sharing your experience. I came to the same conclusion, with less real data to back my opinion up. For medium bore rifles, I now have settled on a couple of .375's, a 9.3x62 and a 9.3x74R. I skipped over the .338 because its "extended range" abilities are of no interest to me since I have no desire to shoot an unwounded big game animal that is over 300 Meters away. I am perfectly satisfied.

Well perhaps not perfectly, I do still fool around with a .35 Whelen and a .450-400 Nitro Express 3".... :-)