I'm leaning toward my Tikka Superlight in 243 loaded with either 95 grain Nosler Ballistic Tips or 80 grain TTSX for opening day. No other reason except I've always taken out a 30-06 of one flavor or another and maybe it will change my luck.
On the other hand, I can only shoot 1 buck and no doe tag this year so I would hate to tag out opening day and leave all my other rifles in the safe. I usually take everything out at least once a season.

Wag more, bark less.

The freedoms we surrender today will be the freedoms our grandchildren will never know existed.

The men who wrote the Second Amendment didn't just finish a hunting trip, they just finished liberating a nation.