I've loaded a lot of 243's over the years for deer hunting. For some reason or another, my most accurate loads have always been with the 85-95 grain bullets. I've never been able to get the accuracy I'm looking for out of a 100 grain bullet. My son has killed a number of deer, including a couple of big bucks, using the 85 grain Sierra BTHP, as his Model 700 really likes that bullet. I load it with an over max dose of W760, and it's really moving on. In the rifle my grandkids use, a Youth Model 700, I use a 95 SST or a 100 soft point. In my 243 LVSF, I like the 90 or 95 grain Noslers if I can find them, which I've not been able to as of late, so I use the 95 grain SST.

The 243 is no different from any other chambering, just put a good bullet where it's supposed to go, and it'll do the job. It's really not rocket science.