My favorite is probably the .340, just because it is the only Weatherby cartridge that I have spent any real time with. I think I killed caribou, elk, mule deer, whitetail and black bear with it, plus smaller critters. Spire points and accubonds if I remember correctly. I finally traded it off a couple years ago as I just didn't like dealing with the recoil and that multi lug Mark V action didn't impress me much. It was heavy too.
I really don't miss it, though it hit critters (and myself) with authority.
