I had these two at the range yesterday. A Ruger flattop convertible with the 45 colt cylinder in it and my M25-5.
My pick would be the Ruger with either cylinder. The .45acp is a little more accurate than the .45 colt, but not enough to complain about. With my reloads they hit the same POI at 15 yards the .45acp kicks less.
The M25-5 is pretty accurate and handsome as can be but big and heavy. Mine is a 6” barrel, a 4” might be better.
Could use my 1911 but I reload and brass all over the woods is not what I want. There are lots of targets of opportunity and do not want to pick up brass.
Find a friend and shoot his guns if possible, then make your choice.

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