My friend shot a mature bull at 30 yards with his 25-06 in 2001. Took the first shot to the lungs, second to the shoulder area while departing, and a third one in the neck, killing it. Load was a 120 gr. Speer Grand Slam handload. The only shot to exit was the broadside lung shot. It killed the bull, but who knows how far it could of gone if he didn't break its neck.

I don't suggest a 25-06 for elk, but it will work with very good bullets, and excellent shooting. 100 & 115 gr. X bullets, 120 gr. Swift A-Frames, and 115 gr. TBBCs would be the only bullets I'd sling at an elk from a 25 cal. Better yet to go to a 28 cal, and shoot a premium 160 or 175 gr.