Both hornady and sierra round nose bullets work the same on game. Buy whichever one you can find. There isnt a better bullet for on game performance when it comes to deer size game. They out perform a spitzer bullet in every way when you want an animal down on the ground as fast as possible. Dont let velocity scare you either. I've used them in everything from 3006 up to 30 nosler. They just flat out work and have been one of the most popular bullets in the mountains here for many, many years. Rem 7600 in 3006 with 180 gn round nose is the official deer setup for central pa woods