I shoot deer regularly with a suppresser since they became legal in Michigan....for shots under 70 yards....Cutting Edge Bullets 250 gr. .452 Handgun Raptor with a plastic tip in a Christensen Arms 450 Bushmaster doing just over 1000 fps....its so quiet you can hear the bullet impact....
I have shot bucks feeding that the other deer with them didn't run at the shot....

Suppressers are great for deer control shooting....I have shot several at under 50 yards using one....