I conclude a small high velocity FMJ bullet can brain an elephant, maybe a rino, or even a Cape Buffalo. However, a big bore hitting a big bear broadside will make a hole for them to bleed out through the muscle and fat. Same with plains game. Big hole in the chest makes them bleed out faster, trail easier to follow. A small bore must hit exactly where needed for a clean kill.
I've read in Africa, they want big bores to follow blood trails in the dirt and dust.
