I have Michelin Defender LTX on my F250 and will continue buying the same. For my Toyota 4runner, I'm on my 3rd set of Yokohama Geolander and have been very happy with them.
How do your LTX's do in the mud?
I'm mainly highway and dirt ranch roads. No mud. I don't expect they'd be good in mud, not a very aggressive tread. Which is fine with me, I don't expect to do any mud off-roading with a crew cab diesel long bed. That's a recipe for being stuck, really bad.
