I used a 220 grain Nosler partition out of my 30-06 on my only moose. Bull trotted a few steps after first shot, dropped on quick follow up. It did the job but I did recover one bullet and was not impressed with weight retention (less than 50%). It surprised me as I’ve heard nothing but positive things about partitions. Hoping to hunt moose again someday. Working on loads for my 358 Win and a new to me 338 win mag…
The front half of a NP is supposed to act like a soft point until it expands to the partition. This gives it predictable expansion.
You might be better off with a Barnes X if you want higher weight retention.
