I’m a lefty, every semiautomatic I have tried in my left front pocket has had issues with the magazine release occasionally getting pressed in pocket carry. Not all the time but enough to make me lose confidence.

OTOH pocket carry is where an Airweight shines.

"...if the gentlemen of Virginia shall send us a dozen of their sons, we would take great care in their education, instruct them in all we know, and make men of them." Canasatego 1744