I shot a bull moose in Newfoundland with a 338RUM and a 250gr Accubond bullet. The moose was hit on the point of the shoulder and it flipped him over backwards, DRT. The bullet penetrated both shoulders and was captured in the off-side hide. The expanded bullet weighed 140gr after tearing through all of that bone.
My opinion - use a 200gr Accubond/Partition or similar bonded bullet just in case you encounter a lot of bone.
