I shot a couple crop damage deer with a 250 gr TTSX from my 375 H&H Mag loaded at 2800 fps. Shots were 150 and 160 yards, tight behind the shoulder with exits through the slats on the off side. Both dropped at the shot. Plenty of expansion, exits were the size of a golf ball.
I had similar experience with the 250 TTSX, though started @ 3130 mv. They were quite effective….looking forward to using my 270 LRX’s @ 3100. They should do pretty good also! memtb