I shoot the 110g TTSX in the 270 Winchester, Win 760, H4350m and R#17, they perform flawlessly.

IN the 7 Rem Mag, I have shot the 120 and 140g TTSX on top end pressure loads with IMR4350 with the 140 and R#22 with the 120s. Both bullets are very, very accurate seated .050 away from the lands. I do feel like the 140g TTSX, when started with a MV of 3250 leaves much less shock on a white tail at a range of 450 yards. A buddy was shooting the 120g TTSX in his custom short freebore 7 STW at 3850 with excellent accuracy. He shot a 100 lb doe and the bullet did not expand, impact 550 yards.

It is just my gut feeling that the Mono's need impact velocity to do their best work, or a large animal.

I would be tempted to use an 80g TTSX in a 25/06, same with a 243 Winchester.