I used only my 375 H&H.....It absolutely hammered everything, and without fuss. AD
I have never hunted with or even fired a 375 anything but I am sure that it would hammer everything. I had a 35/06 AI for a while and it certainly was a lead slinger.
Soon, I think I will have me a 375 Ruger. I like the idea of 270 gr bullets.
Good luck on your trip.