SW - You'll get advise from more experienced handgun hunters than me but for what it's worth, I'd get a Ruger Blackhawk in .45 Colt. I haven't been read a new reloading manual but my old ones give two .45 Colt loads. One for old revolvers and one for Rugers which are much stronger.
I'm not sure if Ruger still makes convertible .45s with two cylinders .45 ACP and .45 Colt. That might fill the bill.
