I like the 100gn Hornady bullet and 48gn H4350. However, I recently loaded some 100gn Swift Sciroccos with 47gn H4350. I shot a feral billy goat with it and he dropped on the spot. The 100gn Scirocco penetrated diagonally through the goat and exited down his left ribcage leaving a hole about the size of a 20c piece (about an inch). Very happy with performance like that.