My friend runs a camp in Maine, he likes hunters to use a 30 cal or larger, 180 gr or larger bullet, (not necessarily a cannon, he's fine with 308s, 35 rem, 06 and the like) and recommends no shoulder shots. However as a guide he deals with sportsman of all abilities, so guides need to give themselves a little edge since they will be the ones chasing wounded bears. Only shot one smaller one myself with a 300 weatherby that went 20 yds. Hope to chase them again this year in Maine.