For myself, they one I got deer with last year.. They all can work for the most part. The one I have taken the most deer with? A 8x57 WWII Mauser with a peep site.. Second would be a CZ550 in 9.3X62.. My favorite? A 6.5X55 Swede. Depends on the year and the hunting area. They are all good when one gets meat in the freezer..