Personally ive shot deer with 270,280,30-06,7mm08,308,7 remmag,300winmag,3030,444marlin,& 45-70.
I own several diffrent calibors i use in diffrent situations but more and more i find myself toteing my rem 700 7mm08 loaded with 139gr interlocks. I honestly cant think of a better all around deer round that has the ability to take any deer from close to far and not beat you to death doing it.