I have used the TTSXs in 7mm, 270, 30 cal, and the 375 with uniform success at ranges from about thirty yards to right at five hundred. I have recovered only two.

The five hundred yard shot was with a 150-gr TTSX from a 284 Win started at 2900 fps. The deer was hit through the heart on a broadside shot without impacting any ribs. The exit would barely accept my little finger tip.

Though that is an example of one out of maybe twenty, I'll let you draw your own conclusions but I've gone to the 140 in the 284 at about 3100 fps.